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Vertex Pharmaceuticals (NASDAQ: VRTX) — Company Overview, News & Financial Data

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Company profile

Vertex Pharmaceuticals

Vertex Pharmaceuticals is a global biotechnology company engaged in discovering, developing, and commercializing transformative medicines for people with serious diseases. The company focuses on scientific innovation to treat life-threatening conditions, with a primary commercial focus on transformative therapies for cystic fibrosis. Beyond cystic fibrosis, the business advances a broad clinical research pipeline spanning gene-editing therapies for sickle cell disease and transfusion-dependent beta thalassemia, non-opioid pain treatments, APOL1-mediated kidney disease therapies, and cell therapies for type 1 diabetes. Operating research laboratories and commercial offices globally, the organization partners with research institutions to expand healthcare solutions.

Snapshot

Public USOwnership
1989Year founded
5,001–10,000Employees
Boston, United StatesHead office
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Global footprint

Operations

Products and/or services of Vertex Pharmaceuticals

  • Cystic Fibrosis Treatments: Development and commercial supply of oral small-molecule CFTR modulator therapies including triple and dual combination regimens designed to treat the underlying cause of cystic fibrosis across global markets for pediatric and adult patient populations.
  • Gene-Edited Cell Therapies: Ex vivo CRISPR-Cas9 gene-edited cellular treatments authorized for patients with severe sickle cell disease and transfusion-dependent beta thalassemia, administered through specialized qualified treatment centers in North America and Europe.
  • Non-Opioid Pain Therapies: Selective small-molecule NaV1.8 voltage-gated sodium channel inhibitors for the management of moderate-to-severe acute pain, offering alternative non-opioid pain treatment options in acute care, surgical, and outpatient medical settings.
  • Kidney Disease Pipeline: Clinical-stage small molecule drug candidates targeted at treating APOL1-mediated kidney disease and IgA nephropathy, aiming to reduce proteinuria and slow progressive renal function loss in patients worldwide.
  • Type 1 Diabetes Therapies: Allogeneic and autologous stem cell-derived fully differentiated insulin-producing islet cell therapies, evaluated in clinical trials to restore endogenous insulin production and glycemic control without requiring chronic immune suppression.
  • Endocrine and Metabolic Programs: Development of targeted small molecule therapies for rare endocrine and metabolic diseases, expanding clinical development into specialized endocrinology and therapeutic areas through internal research and strategic acquisitions.

Vertex Pharmaceuticals executive team

  • Jeffrey Marc LeidenExecutive Chairman
  • Reshma KewalramaniCEO, President & Director
  • Charles F. Wagner Jr.Executive VP, COO & CFO
  • Amit K. SachdevExecutive VP & Chief Patient and External Affairs Officer
  • Ourania TatsisExecutive VP & Chief Product Affairs Officer
  • Carmen BozicExecutive VP of Global Medicines Development & Medical Affairs and Chief Medical Officer
  • Kristen C. AmbroseSenior VP & Chief Accounting Officer
  • Mark BunnageExecutive VP & Chief Scientific Officer
  • Susie LisaSenior Vice President of Investor Relations
  • Joy LiuEVP, Chief Legal Officer & Corporate Secretary

Key financials

Reported results for Vertex Pharmaceuticals, in USD.

Market cap
136.9B
Revenue (TTM)
12.6B
P/E ratio
31.5
EPS (diluted, TTM)
17.2
Dividend yield
—
Profit margin
35.0%
Vertex Pharmaceuticals annual revenue and income
Fiscal year endRevenueOperating incomeNet income
12.1B4.8B4B
11B-232.9M-535.6M
9.9B3.8B3.6B
8.9B4.3B3.3B