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Vaxcyte Inc (NASDAQ: PCVX) — Company Overview, News & Financial Data

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Company profile

Vaxcyte Inc

Vaxcyte Inc is a clinical-stage vaccine innovation company focused on developing high-fidelity, broad-spectrum conjugate vaccines to prevent or treat bacterial infectious diseases. Utilizing a cell-free protein synthesis platform and site-specific protein conjugation technology, the company engineers vaccine candidates aimed at overcoming the limitations of conventional cell-based vaccine approaches. Its lead pipeline assets target invasive pneumococcal disease, including VAX-31 and VAX-24, as well as early-stage candidates targeting Group A Streptococcus, Shigella, and periodontitis. Headquartered in San Carlos, California, Vaxcyte maintains research, development, and biomanufacturing operations in the United States to support clinical production and commercial supply.

Snapshot

Public USOwnership
2013Year founded
501–1,000Employees
San Carlos, United StatesHead office
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Global footprint

Operations

Products and/or services of Vaxcyte Inc

  • Pneumococcal Conjugate Vaccine VAX-31: A 31-valent conjugate vaccine candidate engineered to protect adults and infants against invasive pneumococcal disease, offering broader serotype coverage than existing licensed vaccines and advancing through Phase 3 clinical development.
  • Pneumococcal Conjugate Vaccine VAX-24: A 24-valent conjugate vaccine candidate developed to prevent invasive pneumococcal disease, completing clinical trials across adult and pediatric populations while demonstrating broad serotype immunogenicity and favorable safety profiles.
  • Cell-Free Protein Synthesis Platform: An advanced biopharmaceutical platform utilizing cell-free protein expression and site-specific conjugation to produce multi-valent conjugate vaccines without the yield and structural limitations inherent to traditional cell-based manufacturing approaches.
  • Group A Strep Vaccine Candidate: A preclinical vaccine candidate targeting Group A Streptococcus bacterial infections, designed to provide broad-spectrum protection against severe invasive disease, rheumatic heart disease, and acute pharyngitis in children and adults globally.
  • Shigella Vaccine Candidate: A novel bioconjugate vaccine candidate under early-stage development to combat Shigella bacterial infections, aiming to prevent bacillary dysentery and severe endemic diarrheal disease in young children and high-risk populations.
  • US Biomanufacturing Infrastructure: Clinical and commercial vaccine manufacturing operations located across the United States, including dedicated production capacity and a major biomanufacturing facility expansion in North Carolina to support future global supply demands.

Vaxcyte Inc executive team

  • Mr. Grant E. Pickering M.B.A.Co-Founder, CEO & Director
  • Mr. Andrew L. Guggenhime M.B.A.President & CFO
  • Mr. James Wassil M.B.A., M.S.Executive VP & COO
  • Mr. Mikhail Eydelman J.D.Senior VP, General Counsel, Chief Compliance Officer & Corporate Secretary
  • Dr. Jeff Fairman Ph.D.Co-Founder & VP of Research
  • Ms. Whitney JonesChief People Officer
  • Ms. Janet GraesserSenior Vice President of Corporate Affairs
  • Mr. Harp Dhaliwal M.B.A.Chief Technical Operations Officer
  • Sam IkiSenior Vice President of Project Management
  • Ms. Elvia CowanSenior Vice President of Finance