
About Karyopharm Therapeutics
Karyopharm Therapeutics (NASDAQ:KPTI) focuses on the discovery, development, and commercialization of novel first-in-class drugs for the treatment of cancer and other major diseases. With a keen emphasis on innovative therapeutic approaches, the company aims to tackle unmet medical needs, particularly in the oncology sector. Projects spearheaded by Karyopharm often revolve around the utilization of its proprietary SINE technology, designed to modulate nuclear export signals critical in cancer cell proliferation and survival. Their flagship product, selinexor, has made significant impacts in the treatment landscape for multiple myeloma and diffuse large B-cell lymphoma, marking strides towards achieving their objective of transforming cancer care. Through rigorous research and development, Karyopharm strives to expand its portfolio and impact across various cancer types, underscoring its commitment to advancing healthcare solutions.
Snapshot
Operations
Produtos e/ou serviços de Karyopharm Therapeutics
- XPOVIO (selinexor) - First and only XPO1 inhibitor for multiple myeloma and diffuse large B-cell lymphoma.
- Clinical trials for selinexor in various cancer types - Expanding the potential use of selinexor in oncology.
- Eltanexor development - A second-generation SINE compound with potential for treating myelodysplastic syndromes.
- KPT-9274 - Dual PAK4/NAMPT inhibitor, focused on non-Hodgkin's lymphoma and solid tumors.
- Research on new SINE compounds - Innovating more selective inhibitors targeting the XPO1 cancer pathway.
- Partnerships for drug development and commercialization - Collaborating to enhance global reach and accelerate drug development pipelines.
equipe executiva do Karyopharm Therapeutics
- Mr. Richard A. Paulson M.B.A.President, CEO & Director
- Ms. Sohanya Cheng M.B.A.Executive VP, Chief Commercial Officer & Head of Business Development
- Dr. Reshma Rangwala M.D., Ph.D.Executive VP, Chief Medical Officer & Head of Research
- Dr. Sharon Shacham M.B.A., Ph.D.Co-Founder & Chairman of Scientific Advisory Board
- Ms. Kristin AbateVP, Chief Accounting Officer & Assistant Treasurer
- Mr. Michael J. Mano J.D.Senior VP, General Counsel & Secretary
- Mr. James Accumanno J.D.Chief Compliance Officer
- Ms. Lisa DiPaoloExecutive VP & Chief Human Resource Officer
- Mr. Brian AustadSenior Vice President of Pharmaceutical Sciences
- Mr. Stuart PoultonExecutive VP & Chief Development Officer