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Neurocrine reports positive 2-year pediatric CAH data
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Neurocrine reports positive 2-year pediatric CAH data

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  • Neurocrine Biosciences (NASDAQ:NBIX) reported two-year Phase 3 CAHtalyst study data showing improved growth and metabolic health for children treated with CRENESSITY.
  • Children with advanced bone age saw a mean bone age reduction of 1.12 SDS and a 4.7 cm gain in predicted height.
  • The company stated that the treatment enabled sustained glucocorticoid reductions, which improved insulin resistance and body mass index measurements.

Neurocrine Biosciences (NASDAQ:NBIX) presented two-year pediatric data for its CRENESSITY therapy at the ENDO 2026 medical conference.

This study evaluated children with classic congenital adrenal hyperplasia, a condition that often requires high-dose steroid treatment.

Caregivers surveyed in the study reported 100% overall satisfaction and high levels of optimism regarding their children's future health outcomes.

The company stated the treatment was well-tolerated with no new safety signals, and following the announcement, Neurocrine's share price was up at $121.45.

Neurocrine focuses on developing treatments for neurological, endocrine, and psychiatric disorders to address significant gaps in patient care.

The company continues to advance its clinical pipeline through various late-stage trials targeting hormonal regulation and rare disease treatment.