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EU approves Astrazeneca's Enhertu for HER2 positive metastatic solid tumors

Daiichi Sankyo and AstraZeneca (NASDAQ:AZN) announced that Enhertu (trastuzumab deruxtecan) has been approved in the European Union as monotherapy for the treatment of adult patients with unresectable or metastatic HER2 positive (IHC 3+) solid tumors who have received prior treatment and who have no satisfactory alternative treatment options.

Leia mais: EU approves Astrazeneca's Enhertu for HER2 positive metastatic solid tumors
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BCAL Diagnostics secures extra A$4.9m to fund cancer detection portfolio

BCAL Diagnostics (ASX:BDX), an Australian healthcare company focused on early cancer detection, has secured firm commitments for a further A$4.9 million under its existing A$10 million convertible note facility, with the additional funds to be drawn down as required.

Leia mais: BCAL Diagnostics secures extra A$4.9m to fund cancer detection portfolio
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Albanese Government doubles penalty to $99m as tech giants face under-16 social media scrutiny

The Albanese Government plans to strengthen Australia’s social media minimum age law by giving the eSafety Commissioner broader information‑gathering powers and doubling the maximum penalty for systematic breaches from $49.5 million to $99 million.

Leia mais: Albanese Government doubles penalty to $99m as tech giants face under-16 social media scrutiny
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Security software stocks face a fresh profit test

  • BlackBerry reported Q1 FY2027 revenue of $152.9 million, up 26% year over year, with adjusted EBITDA of $36.3 million and GAAP operating income of $15.3 million.
  • The comparison group shows a wide revenue gap, from Cerence’s $64.2 million quarterly revenue to Palo Alto Networks’ $3 billion quarterly revenue.
  • The main sector test is whether AI security, connected-vehicle software, and government communications can keep growing while margins stay under control.
Leia mais: Security software stocks face a fresh profit test
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How escalating artificial intelligence hardware demand is rewriting memory chip valuations

  • Micron Technology reported $41.46 billion in quarterly revenue as the firm capitalized on surging data center component demand.
  • The semiconductor manufacturer recorded a GAAP net income of $28.24 billion and declared a quarterly dividend of $0.15 per share.
  • Global hardware manufacturers must carefully secure raw materials to execute aggressive revenue projections amid volatile enterprise capital expenditures.
Leia mais: How escalating artificial intelligence hardware demand is rewriting memory chip valuations
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How global delivery networks are quietly sacrificing scale to protect operational margins

  • FedEx reported $25 billion in fourth-quarter fiscal 2026 revenue while executing a spin-off of its freight division to consolidate core operations.
  • The logistics provider exceeded cost-cutting targets by securing over $1 billion in structural savings and achieving an adjusted earnings per share of $6.60.
  • Global transportation firms face mounting pressure to offset mixed profitability trends by heavily reducing capital spending and divesting secondary business units.
Leia mais: How global delivery networks are quietly sacrificing scale to protect operational margins
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Why dominant pharmaceutical firms are paying billion-dollar premiums for immunology assets

  • AbbVie agreed to acquire Apogee Therapeutics in a $10.9 billion all-cash transaction, paying a 60% premium to secure a late-stage immunology pipeline.
  • The company will pay $135.11 per share, with executives projecting the deal will not become accretive to adjusted earnings until 2032.
  • Large pharmaceutical manufacturers face intense capital pressure to acquire unproven, long-acting biologics to offset impending revenue losses from patent expirations.
Leia mais: Why dominant pharmaceutical firms are paying billion-dollar premiums for immunology assets
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WiseTech shares plunge amid federal fraud investigation

  • Federal authorities are investigating WiseTech Global (ASX:WTC) executive chairman Richard White over visa fraud and human trafficking allegations.
  • The ongoing controversy triggered a sharp market sell-off, pulling the WiseTech share price down to $36.88.
  • Institutional investors are reassessing sector governance and operational risk amid wider software industry headwinds.
Leia mais: WiseTech shares plunge amid federal fraud investigation
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Replimune receives FDA acceptance of resubmitted BLA for RP1 in advanced melanoma

Replimune (NASDAQ:REPL) announced that the U.S. Food and Drug Administration has accepted for review the company’s resubmitted Biologics License Application for RP1 (vusolimogene oderparepvec) in combination with nivolumab for the treatment of advanced melanoma.

Leia mais: Replimune receives FDA acceptance of resubmitted BLA for RP1 in advanced melanoma